NEW YORK (PIX11) — In a violent weekend across the city, at least 23 people were shot or stabbed throughout the five boroughs since Friday, with at least six of those victims dying, according to authorities. Perhaps the most shocking incident, however, was one in which no injuries were reported.

Gunfire rang out Sunday evening near storied St. Patrick’s Cathedral, a perennially popular spot for tourists in bustling Midtown Manhattan, police said.

Two groups were playing the three-card monte card game near East 50th Street and Madison Avenue around 6 p.m. when a dispute broke out between them, officials said.

One person from among the fray pulled out a gun and fired a single shot, authorities said. The shot struck a Mercedes, and the gunman and his group fled the scene, police said.

They remained at large, though two men associated with the struck car were taken into custody on outstanding warrants unrelated to the encounter, officials said.

The incident came near the end of a violent weekend across the city, with much of the bloodshed coming in Brooklyn. One person was killed and four others injured in a shooting along the boardwalk in Coney Island around 11:55 p.m. Saturday, according to authorities. And at least another two people were fatally shot across the borough, while a third was left in critical condition from a stabbing, from late Saturday into early Sunday, police said.

Meanwhile in the Bronx, one man was killed and another two wounded in a shooting around 3:50 a.m. Saturday in the Mount Hope section, officials said. Investigators announced early Monday that suspect Roman Anderson, 22, had been formally arrested on charges of murder, manslaughter, assault, and criminal possession of a weapon in connection to that incident.

When asked about crime over the weekend as part of a broader trend, Mayor Eric Adams said families who have lost loved ones should add their voices to his in calling for change in Albany.

“Often times, those perpetrating these crimes are repeated offenders, and we have been clear on that,” Adams said.

However, the mayor also said he would continue to do whatever he could to keep New Yorkers safe.  He said gun arrests and felony arrests are up, and that the NYPD is going after vehicles big and small used in crimes.

Adams has also made it a point to press officers to be more active on patrol and is working to take sworn officers doing clerical work and put them back on the streets.

“Police officers are supposed to be going after bad guys, I said this on the campaign trail,” Adams said.

Submit tips to police by calling Crime Stoppers at 1-800-577-TIPS (8477), visiting crimestoppers.nypdonline.org, downloading the NYPD Crime Stoppers mobile app, or texting 274637 (CRIMES) then entering TIP577. Spanish-speaking callers are asked to dial 1-888-57-PISTA (74782).