Black smoke poured from the chimney fixed to the roof of the Sistine Chapel on Wednesday morning, indicating that the cardinals’ first two votes of the day were inconclusive.
The 115 voting cardinals are taking part in the second day of the secretive conclave to elect a new pope.
They will have two more opportunities to vote later Wednesday.
A two-thirds majority is required to confirm a new pontiff to step into the shoes left empty by the historic resignation of Benedict XVI at the end of last month.
Whoever it may be will take on the leadership of a church that has been rocked by child sex abuse scandals and corruption claims in recent years.